Research Articles
Strategic Microbial Chassis Selection: A Comprehensive Framework for Synthetic Biology in Biomedicine
This article provides a systematic framework for selecting and optimizing microbial chassis in synthetic biology, specifically tailored for researchers and drug development professionals.
Beyond E. coli: How Broad-Host-Range Chassis are Revolutionizing Synthetic Biology
This article explores the paradigm of broad-host-range (BHR) synthetic biology, which repositions the microbial host from a passive platform to an active, tunable design variable.
AI vs. Traditional Strain Optimization: A New Era of Validation, Efficiency, and Biological Relevance
This article provides a comprehensive analysis for researchers and drug development professionals on the paradigm shift from traditional, empirical strain optimization methods to AI-driven, predictive approaches.
Native vs. Heterologous Pathways: A Strategic Guide for Efficient Bioproduction
This article provides a comprehensive comparison of native and heterologous pathway efficiency for researchers and drug development professionals.
A 2025 Strategic Framework for Evaluating Platform Strains in Diverse Chemical Production
This article provides a comprehensive guide for researchers, scientists, and drug development professionals on the systematic evaluation of microbial platform strains for the synthesis of diverse chemicals, including pharmaceuticals.
CRISPR vs. TALEN vs. ZFN: A Comprehensive Guide to Choosing Your Genome Editing Tool
This article provides a detailed comparison of the three major genome-editing platforms—Zinc Finger Nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), and the CRISPR-Cas system.
Enzyme-Constrained vs Stoichiometric Models: A Performance Guide for Biomedical Researchers
This article provides a comprehensive analysis for researchers and drug development professionals on the performance and application of enzyme-constrained metabolic models (ecModels) versus traditional stoichiometric models.
Comparative Analysis of Biofuel Production Yields: Feedstocks, Technologies, and Sustainability Metrics
This article provides a comprehensive, data-driven comparative analysis of biofuel production yields for researchers and scientists.
Bridging the Digital and Physical: A Strategic Guide to Validating Computational Predictions with Experimental Results
This article provides a comprehensive guide for researchers and drug development professionals on the critical process of validating computational predictions with experimental data.
Generational Shift: A Sustainability Comparison of First, Second, and Third-Generation Biofuels
This article provides a comprehensive analysis of the sustainability profiles of first, second, and third-generation biofuels, tailored for researchers and scientists in the bioenergy sector.