Research Articles
Metabolic Engineering of E. coli BL21(DE3): A Powerful Platform for Biopharmaceutical and Biochemical Production
This article provides a comprehensive guide for researchers and industry professionals on leveraging Escherichia coli BL21(DE3) for metabolic engineering.
Mastering Cellular Metabolism: Cutting-Edge Strategies for Dynamic Regulation of Central Carbon Pathways
This comprehensive review explores the latest advances in strategies for dynamically regulating central carbon metabolism, a critical control nexus in cellular physiology.
From Pathways to Predictions: How Dynamic Models of E. coli Central Carbon Metabolism Are Revolutionizing Systems Biology and Biotechnology
This article provides a comprehensive guide for researchers and biotech professionals on dynamic models of central carbon metabolism in Escherichia coli.
From Networks to Novel Therapies: A Modern Guide to Drug Target Discovery Using Metabolic Models
This comprehensive article provides researchers, scientists, and drug development professionals with a detailed roadmap for leveraging metabolic models in drug target identification.
Eliminating Loops in Flux Sampling: Detection Methods and Best Practices for Metabolic Network Analysis
This article provides a comprehensive guide to detecting and removing thermodynamically infeasible loops (TILs) from flux sampling distributions in metabolic network modeling.
A Comprehensive Guide to Debugging Genome-Scale Metabolic Models: From Foundations to Clinical Translation
This article provides a systematic guide for researchers and drug development professionals on debugging genome-scale metabolic reconstructions (GEMs).
Mastering Omics Integration: A 2024 Guide to Data Normalization Methods for Multi-Omics Analysis
This comprehensive guide provides researchers, scientists, and drug development professionals with a detailed framework for data normalization in multi-omics integration.
Optimizing Bioreactor Performance: A Comprehensive Guide to DO-Stat Control for Enhanced Substrate Feeding in Biopharmaceutical Production
This article provides a thorough examination of Dissolved Oxygen Stat (DO-Stat) control for substrate feed rate regulation in bioreactors, tailored for researchers, scientists, and drug development professionals.
Engineer Biology: A Guide to Modern DNA Assembly Methods for Synthetic Pathway Construction
This comprehensive guide explores contemporary DNA assembly methods for constructing synthetic pathways, a cornerstone of synthetic biology and metabolic engineering.
Mastering DBTL Cycles: A Complete Guide to Accelerated Strain Improvement for Drug Development
This comprehensive guide explores the Design-Build-Test-Learn (DBTL) framework for microbial strain improvement, tailored for researchers and drug development professionals.